Re: "Zinc lozenges and vitamin C for the common cold are not examples of placebo effect in action".
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چکیده
منابع مشابه
Zinc lozenges reduce the duration of common cold symptoms.
A randomized, double-blind, placebo-controlled clinical trial has shown that treatment of the common cold with zinc gluconate lozenges resulted in a significant reduction in duration of symptoms of the cold. Patients received zinc-containing lozenges or placebo lozenges every 2 hours for the duration of cold symptoms. The median time to complete resolution of cold symptoms was 4.4 days in the z...
متن کاملZinc lozenges and the common cold: a meta-analysis comparing zinc acetate and zinc gluconate, and the role of zinc dosage
OBJECTIVE To compare the efficacy of zinc acetate lozenges with zinc gluconate lozenges in common cold treatment and to examine the dose-dependency of the effect. DESIGN Meta-analysis. SETTING Placebo-controlled zinc lozenge trials, in which the zinc dose was > 75 mg/day. The pooled effect of zinc lozenges on common cold duration was calculated by using inverse-variance random-effects metho...
متن کاملZinc Acetate Lozenges May Improve the Recovery Rate of Common Cold Patients: An Individual Patient Data Meta-Analysis
BACKGROUND A previous meta-analysis of 3 zinc acetate lozenge trials estimated that colds were on average 40% shorter for the zinc groups. However, the duration of colds is a time outcome, and survival analysis may be a more informative approach. The objective of this individual patient data (IPD) meta-analysis was to estimate the effect of zinc acetate lozenges on the rate of recovery from col...
متن کاملZinc acetate lozenges for treating the common cold: an individual patient data meta-analysis.
AIMS The aim of this study was to determine whether the allergy status and other characteristics of common cold patients modify the effects of zinc acetate lozenges. METHODS We had available individual patient data for three randomized placebo-controlled trials in which zinc acetate lozenges were administered to common cold patients. We used both one stage and two stage meta-analysis to estim...
متن کاملComplementary and alternative medicine for prevention and treatment of the common cold.
OBJECTIVE To review the evidence supporting complementary and alternative medicine approaches to treatment and prevention of the common cold in adults. QUALITY OF EVIDENCE MEDLINE, EMBASE, and the Cochrane Database of Systematic Reviews were searched from January 1966 to September 2009 combining the key words common cold or influenza with echinacea, garlic, ginseng, probiotics, vitamin C, and...
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ورودعنوان ژورنال:
- Journal of clinical epidemiology
دوره 68 12 شماره
صفحات -
تاریخ انتشار 2015